I had this issue. Once you've made sure your ear/head phones are working in other games go back into Blops 2 and go to options, settings, sound, sound device and make sure it's the same as your head phones.

Bussius
@Bussius
I had this issue. Once you've made sure your ear/head phones are working in other games go back into Blops 2 and go to options, settings, sound, sound device and make sure it's the same as your head phones.