Plutonium

I have the issue that Plutonium wont start my game even though I did all thats explained in all support feeds. I start Plutonium, then start the game. Plutonium closes itself and nothing happens. I have excluded the folder of the game and Plutonium from my firewall and did everything else, nothing helps.
When i try to open a Mod in the normal game it also crashes and says it could'nt load some image. It doesnt matter which zombie map i am trying to play its the same every time. I have installed T4M and everything but it still does not work. can anybody help me?