Same here, my mouse doesn't show up in-game, and the console keeps saying something about a UI element possibly overwriting something.
I've tried doing a variety of things such as...
-Re-downloaded the launcher
-Re-torrented the data files
-Deleted the Plutonium folder in Appdata
-Made sure "improve pointer precision" and "enable pointer trails" were both disabled in control panel settings (other thread said they were possible culprits)
-Switched between windowed, fullscreen, windowed fullscreen (other thread also said this to be a possible culprit)
-Reset all my settings in-game
-Disabled every overlay from external programs
-Closed as much background apps as I could
-Ran the program as administrator
-Gave it "Very High" CPU priority via Process Lasso
-Disconnected & reconnected my mouse, also tried a different USB port
-And most importantly, I turned my pc off and back on again
...and still, nothing worked.
Plutonium has worked perfectly fine for me previously on the same system a few months ago, only difference is that I wiped my old windows install since then, but that should minimize problems, not create more of them.
Some info for any devs wondering, I'm running Plutonium r3417, using the data files from the torrent link present on the installation guide as of 2023-May-12. I'm also running the latest version of Windows 10 Pro, 22H2 build 19045.2965.
My mouse is a Logitech G502, I don't have Logitech GHUB installed (doing so hasn't caused me any issues and saves me a gig of space)